For these engaged in opioid agonist remedy (OAT), cannabis might be an efficient technique to scale back fentanyl publicity.
That’s the takeaway from a new study printed this month within the journal Drug and Alcohol Dependence.
Drawing knowledge from “two community-recruited potential cohorts of people that use medicine in Vancouver, Canada,” the researchers from the College of British Columbia, Heart of Substance Use mentioned they studied “the connection between hashish use and up to date fentanyl publicity” amongst OAT members between the years 2016 and 2018.
OAT is “an efficient remedy for habit to opioid medicine reminiscent of heroin, oxycodone, hydromorphone (Dilaudid), fentanyl and Percocet,” according to the Canadian research hospital Centre for Addiction and Mental Health, that “includes taking the opioid agonists methadone (Methadose) or buprenorphine (Suboxone)” as a part of an effort to forestall withdrawal and scale back cravings.
The analysis printed in Drug and Alcohol Dependence was primarily based on “819 members on OAT who contributed 1989 observations over the examine interval.” In keeping with the researchers, fentanyl publicity was “frequent.”
“On the baseline interview, fentanyl was detected in a majority of members,” the researchers wrote, saying that it was detected in 53 % of the members, however that total “hashish use was independently related to diminished chance of being not too long ago uncovered to fentanyl.”
“[W]e discovered that amongst greater than 800 members on OAT in Vancouver, Canada, use of hashish was longitudinally related to a considerably decrease threat of being uncovered to fentanyl. Given the magnitude of the overdose disaster within the U.S. and Canada and the substantial contributions of fentanyl to the burden of overdose morbidity and mortality, findings from this examine assist the experimental analysis of cannabinoids as a possible adjunct remedy to OAT to enhance medical outcomes, notably to scale back the danger of relapse to illicit opioid use (i.e., fentanyl) and related threat of overdose and dying,” the researchers wrote, as quoted by NORML.
The Position of Hashish In The Opioid Disaster
The examine is the most recent in a rising physique of analysis to recommend that hashish could also be an efficient weapon within the battle in opposition to the opioid disaster. And because the researchers within the aforementioned examine famous, the “ongoing opioid overdose disaster is pushed largely by publicity to illicitly-manufactured fentanyl.”
In July, a study printed within the journal Systematic Opinions discovered “a a lot greater discount in opioid dosage, diminished emergency room visits, and hospital admissions for continual non-cancer ache by MC [medical cannabis] customers, in comparison with folks with no extra use of MC.”
“There was 64 to 75 % discount in opioid dosage for MC customers and full stoppage of opioid use for continual non-cancer ache by 32 to 59 % of MC customers, when in comparison with sufferers with out extra use of MC,” the researchers of that examine wrote.
And in June, research printed within the Journal of Psychopharmacology discovered “behavioral financial proof that hashish entry could modestly scale back demand for opioids in individuals who’ve ache.”
“Adults reporting present use of opioids for ache administration and previous 30-day hashish publicity…accomplished two hypothetical buy duties during which solely grams of hashish or models of members’ index opioids have been accessible for buy, and two hypothetical duties during which each have been concurrently accessible and the value of 1 drug elevated whereas the opposite was stored fixed,” the researchers wrote.